Gestational Diabetes Pathophysiology. Gestational diabetes mellitus gdm is defined as a glucose intolerance of varying severity with onset or first recognition during pregnancy. The definition of gdm does not preclude the possibility that unrecognized glucose intolerance may have existed before the pregnancy and the definition applies whether insulin oral antidiabetic agents or dietary modification is used for treatment. Insulin a hormone made in your pancreas helps your body use glucose for energy and helps control your blood glucose levels. One main aspect of the underlying pathology is insulin resistance where the body s cells fail to respond to the hormone insulin in the.
In most cases this hyperglycemia is the result of impaired glucose tolerance due to pancreatic β cell dysfunction on a background of chronic insulin resistance. Gestational diabetes is diabetes diagnosed for the first time during pregnancy gestation. According to the 2017 international diabetes federation idf estimates gdm affects 14 of pregnancies worldwide representing 18 4 million births annually. Gestational diabetes mellitus gdm is defined as a glucose intolerance of varying severity with onset or first recognition during pregnancy. Insulin a hormone made in your pancreas helps your body use glucose for energy and helps control your blood glucose levels. Like other types of diabetes gestational diabetes affects how your cells use sugar glucose.
1 gdm develops when insulin secretion fails to.
Gestational diabetes mellitus gdm is a serious pregnancy complication in which women without previously diagnosed diabetes develop chronic hyperglycemia during gestation. In most cases this hyperglycemia is the result of impaired glucose tolerance due to pancreatic β cell dysfunction on a background of chronic insulin resistance. Gestational diabetes mellitus gdm is defined as a glucose intolerance of varying severity with onset or first recognition during pregnancy. Gestational diabetes mellitus gdm is a serious pregnancy complication in which women without previously diagnosed diabetes develop chronic hyperglycemia during gestation. The exact pathophysiology of gestational diabetes is unknown. Gestational diabetes occurs when your body can t make the extra insulin needed during pregnancy.