21
Jan
Pathophysiology Of Hirschsprung Disease. Although the more striking histological feature in hirschsprung s disease is the absence of ganglion cells it is unlikely that this is the only cause of the increased intestinal wall tone provoking a functional intestinal obstruction. At that point the stool moves slowly or stops. One possible etiology of hirschsprung disease is the arrest of aboral neuroblast migration. Hirschsprung s disease hd also known as congenital aganglionic megacolon disease is a congenital disease in which ganglionic cells fail to develop in the large intestine.
Although the more striking histological feature in hirschsprung s disease is the absence of ganglion cells it is unlikely that this is the only cause of the increased intestinal wall tone provoking a functional intestinal obstruction. The basic pathophysiological feature in hirschsprung s disease hd is a functional obstruction caused by a narrowed distal aganglionic colonic segment that prevents the propagation of peristaltic waves. Hirschsprung disease is a birth defect in which nerve cells are missing at the end of a child s bowel. The condition is present at birth congenital as a result of missing nerve cells in the muscles of the baby s colon. In a child with hirschsprung disease stool moves through the bowel until it reaches the part lacking nerve cells. A newborn who has hirschsprung s disease usually can t have a bowel movement in the days after.
At that point the stool moves slowly or stops.
Hirschsprung disease is a birth defect in which nerve cells are missing at the end of a child s bowel. The condition is present at birth congenital as a result of missing nerve cells in the muscles of the baby s colon. One possible etiology of hirschsprung disease is the arrest of aboral neuroblast migration. Hirschsprung s hirsh sproongz disease is a condition that affects the large intestine colon and causes problems with passing stool. Hirschsprung disease is a birth defect in which nerve cells are missing at the end of a child s bowel. This commonly presents as delayed or failed passage of meconium around birth.