What is the etiology of sickle cell anemia

What Is The Etiology Of Sickle Cell Anemia. Sickle cell anemia is caused by a mutation in the gene that tells your body to make the iron rich compound that makes blood red and enables red blood cells to carry oxygen from your lungs throughout your body hemoglobin. Sickle cell anemia arises from a mutation in the hemoglobin gene that causes the blood cells to assume an abnormal shape. Normal red blood cells are round. Sickle shaped red blood cells have trouble passing through the smallest blood vessels and deliver less oxygen to the tissues of the body.

Normal red blood cells are round. Sickle shaped red blood cells have trouble passing through the smallest blood vessels and deliver less oxygen to the tissues of the body. Sickle cell anemia is caused by a mutation in the gene that tells your body to make the iron rich compound that makes blood red and enables red blood cells to carry oxygen from your lungs throughout your body hemoglobin. Sickle cell anemia is a blood disease that affects red blood cells. Learn about the causes symptoms and treatments. Sickle cell anemia is a genetic condition that causes red blood cells to malfunction.

Learn about the causes symptoms and treatments.

In sickle cell anemia valine replaces glutamic acid at the sixth amino acid of the beta globin chain as a result of a recessive single gene mutation. They also increase the risk of blood clots. The specific change in the gene that causes sickle cell anemia is known as the hemoglobin s or hb s mutation. The defect forms abnormal hemoglobin. In sickle cell anemia the abnormal hemoglobin causes red blood cells to become rigid sticky and misshapen. In sickle cell anemia valine replaces glutamic acid at the sixth amino acid of the beta globin chain as a result of a recessive single gene mutation.